Quick Overview

High-purity Ipamorelin, a selective growth hormone secretagogue and ghrelin receptor agonist, synthesized specifically for in vitro laboratory research and development. Formulated as a sterile, lyophilized powder to ensure maximum stability and precision in endocrine, metabolic, and receptor binding assay models.

Product Description

Ipamorelin is a synthetic pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH₂) that acts as a highly selective agonist of the ghrelin receptor (GHS-R1a). Known for its specificity in stimulating growth hormone release without significantly affecting cortisol, prolactin, or ACTH levels at standard experimental thresholds, it has become a vital tool for scientific investigation. In vitro, Ipamorelin is extensively utilized by researchers to study growth hormone secretagogue receptor kinetics, endocrine signaling pathways, and metabolic regulatory mechanisms.

Common Research Applications:

• Receptor Selectivity Studies: Investigating GHS-R1a binding affinity and downstream cellular signaling cascades.
• Endocrine Pathway Analysis: Observing growth hormone secretagogue responses and regulatory feedback mechanisms.
• Metabolic Assay Development: Assessing cellular proliferation and metabolic parameters in specialized culture models.
• Enzymatic Stability: Analyzing the pharmacokinetic and structural advantages of synthetic pentapeptide chains.

Technical Specifications

Storage and Reconstitution

To maintain peptide integrity and stability, please adhere to standard laboratory handling guidelines:

• Lyophilized Form (Dry Powder): Store desiccated at -20°C (or below) upon receipt. While stable at room temperature for brief transit periods, long-term freezing is required to prevent degradation.
• Reconstitution: Reconstitute using bacteriostatic water or sterile water for injection. Introduce the diluent carefully and gently swirl the vial until dissolved. Do not shake vigorously, as this can fracture the peptide bonds.
• Liquid Storage (Reconstituted): Once reconstituted, the solution should be stored at 2°C to 8°C (refrigerated) and utilized within 14 to 30 days. For extended experimental timelines, aliquot the solution into individual vials and freeze at -20°C to avoid repeated freeze-thaw cycles.

Regulatory & Safety Disclaimer