Quick Overview

High-purity Tirzepatide, a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, synthesized specifically for in vitro laboratory research and development. Formulated as a sterile, lyophilized powder to ensure maximum stability and precision in metabolic, receptor binding, and cellular signaling assays.

Product Description

Tirzepatide is a synthetic 39-amino-acid peptide chain incorporating a C20 fatty diacid moiety that enables reversible albumin binding, thereby extending its half-life. As a dual-targeting agonist, it activates both GIP and GLP-1 receptors, triggering synergistic intracellular signaling cascades. In vitro, Tirzepatide is extensively utilized by scientific professionals investigating metabolic homeostasis, dual receptor binding kinetics, insulinotropic pathways, and cellular energy regulation models.

Common Research Applications:

• Dual Receptor Kinetics: Investigating simultaneous GIP and GLP-1 receptor binding affinities and downstream intracellular signaling activation.
• Metabolic Pathway Studies: Observing cellular glucose homeostasis, insulinotropic mechanisms, and energy expenditure dynamics.
• Pharmacokinetic & Half-Life Analysis: Assessing the structural stabilization benefits of the C20 fatty diacid chain and albumin-binding properties.
• Assay Optimization: Evaluating peptide stability, degradation resistance, and receptor desensitization models in culture environments.

Technical Specifications

Storage and Reconstitution

To maintain peptide integrity and stability, please adhere to standard laboratory handling guidelines:

• Lyophilized Form (Dry Powder): Store desiccated at -20°C (or below) upon receipt. While stable at room temperature for brief transit periods, long-term freezing is required to prevent degradation.
• Reconstitution: Reconstitute using bacteriostatic water or sterile water for injection. Introduce the diluent carefully and gently swirl the vial until dissolved. Do not shake vigorously, as this can fracture the peptide bonds.
• Liquid Storage (Reconstituted): Once reconstituted, the solution should be stored at 2°C to 8°C (refrigerated) and utilized within 14 to 30 days. For extended experimental timelines, aliquot the solution into individual vials and freeze at -20°C to avoid repeated freeze-thaw cycles.

Regulatory & Safety Disclaimer